antibiotics

News Story

02/12/2010

For years, doctors have warned patients to finish their antibiotic prescriptions or risk a renewed infection by a "superbug" that can mount a more powerful defense against the same drug. But a new study by Boston University biomedical engineers indicates that treating bacteria with levels of antibiotics insufficient to kill them produces germs that are cross-resistant to a wide range of antibiotics.

In the Feb. 12 issue of Molecular Cell, research led by Boston University Professor James J. Collins details for the first time the biomolecular process that produces superbugs. When administered in lethal levels, antibiotics trigger a fatal chain reaction within the bacteria that shreds the cell's DNA. But, when the level of antibiotic is less than lethal the same reaction causes DNA mutations that are not only survivable, but actually protect the bacteria from numerous antibiotics beyond the one it was exposed to.More »

12/21/2009

A new study led by a team of researchers at New York Medical College suggests that that medical liability concerns may be playing a role in the increase of MRSA in health care settings by encouraging clinicians to prescribe antibiotics more often and more broadly than clinical circumstances and evidence-based guidelines warrant.

The study appeared in the September-October issue of the American Journal of Therapeutics.More »

antibiotics
08/22/2009

ScienceDaily — From 1995 to 2006 the rate of antibiotic prescriptions for acute respiratory tract infections decreased significantly, attributable in part to a decline in ambulatory visits for ear infections in young children, according to a study in the August 19 issue of JAMA. But prescription rates for broad spectrum antibiotics, namely azithromycin and quinolones, increased substantially during the study period.More »

07/22/2009

ScienceDaily — More and more bacterial stems are developing resistance to previously life-saving antibiotics. Physicians have been warning that fatality rates from infections could increase dramatically in the very near future. Researchers at the Technische Universität München (TUM) have now cast light on a metabolic step that appears in many aggressive microorganisms like tuberculosis or malaria pathogens and that may provide a promising target for a new class of antibiotics.More »

antibiotics
07/02/2009

(HealthDay News) -- Repeated use of antibiotics to treat acute ear infections in young children increases the risk of recurrent ear infections by 20 percent, according to researchers in the Netherlands who called for more prudent use of antibiotics in young children.More »

07/02/2009

ScienceDaily (July 2, 2009) — It’s common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it’s unclear which antibiotics are the most disruptive, and if the full array of “good bacteria” return promptly or remain altered for some time.More »

06/26/2009

Many pharmacists recommend cranberry juice consumption in conjunction with low-dose oral antibiotics for prophylaxis for recurrent urinary tract infections (UTIs). So, is this a good idea, since there have been reports of pharmacokinetic interactions between cranberry juice and β-lactams? According to researchers from the University of Washington,More »

06/10/2009

ScienceDaily (June 9, 2009) — A synthetic DNA binding compound has proved surprisingly effective at binding to the DNA of bacteria and killing all the bacteria it touched within two minutes. The DNA binding properties of the compound were first discovered in the Department of Chemistry at the University of Warwick by Professor Mike Hannon and Professor Alison Rodger (Professor Mike Hannon is now at the University of Birmingham). However the strength of its antibiotic powers have now made it a compound of high interest for University of Warwick researchers working on the development of novel antibiotics.More »

antibiotics, DNA
05/29/2009

ScienceDaily (May 29, 2009) — Penicillin and other antibiotics in the beta-lactam family work as well as other antibiotics to treat MRSA (methicillin-resistant Staphylococcuss aureus) infections in the skin and soft-tissue of children and may help prevent further resistance to antibiotic treatment, according to a new study.More »

Patient Guides

09/14/2007
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Vaginitis is an inflammation of the vaginal tissue that can be accompanied by intense itching, pain, and discharge. One of the most common causes of vaginitis is an overgrowth of Candida albicans, a fungus often found in the vagina in small quantities. The acidic environment of the vagina keeps the growth of Candida albicans under control by allowing protective bacteria to flourish. If this environment changes, the balance between fungus and bacterial growth can lead to fungal overgrowth and inflammation.More »

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